Yes, there is a calorie difference between walking one mile and running one mile.
The number of calories burned during exercise depends on several factors, including the intensity of the exercise, the duration of the activity, the body weight of the person, and their fitness level. Running is a higher intensity activity than walking and requires more energy and effort. Therefore, running one mile burns more calories than walking one mile.
The exact number of calories burned during running or walking depends on the factors mentioned above, as well as the pace of the activity. However, on average, running burns approximately twice as many calories per mile as walking. For example, a 150-pound person would burn about 100 calories walking one mile at a moderate pace, but would burn about 200 calories running one mile at a moderate pace.